Fat cell hyperplasia

[coreJack]

Anyone look into this?

Here's what I know (pls correct any errors):
1. Number of fat cells is determined by the time you reach adulthood . . .

2. Unless you gain a lot of weight in adulthood b/c each fat cell can only hold so much fat. If all the existing fat cells are getting full, the body produces new fat cells.

3. Fat cells are permanent. This sounds like bullshit to me. Cells die all the time, with the exception of things like nerve cells. If you lose the fat, why would the body keep around a bunch of unused fat cells forever (i.e., there must be some maintenance cost to upkeep the cell, and if it's not being used, seems to me the body would get rid of it). What I can buy is that unused fat cells stick around longer than unused muscle cells, as the latter have a higher maintenance cost.

4. Fat cells are highly variable in size, so if you lose the fat, having lots of empty fat cells won't make you look pudgy (bodybuilders are an example, though their blood chemistry is so altered, who knows if that's a relevant example).

5. Having more fat cells means it's easier to get fat. I.e., the more fat cells you have, the more readily your body stores fat. Might this be relevant to bulking strategies? Or do the benefits of relatively fast bulking outweigh any cons related to fat cell hyperplasia?

[lylemcd]

1. No. ther are a few critical periods where you can gain new fat cells. Getting fat fucked as an adult is one of them for teh reasons utlined in

2. Yup. If fat cells get too big, they release compounds such as prostaglandins and prostacylins that recruit preadipocytes which mature into adult fat cells. Which are yours to keep.

3. Fat cells can die but it's usually only under extreme conditions such as cancer wasting and a handful of others. For the most part, fat cells are yours to keep short of lipo or something

4. Depends on how many cells you have. Even emptied, fat cells take up some space.

5. A larger number of fat cells is associated with relatively greater risk of diet failure and fat regain, yes. Whether or not fast bulking is a 'problem' will probably depend on
a. how many fat cells you hav
b. how fat you are

If you're lean, the odds of making new fat cells seem fairly small. Yours aren't that full. IF you're already fat and bulk quickly and get truly fat fucked, you may make new fat cells that aren't going away ever.

[coreJack]

If you're lean, the odds of making new fat cells seem fairly small. Yours aren't that full. IF you're already fat and bulk quickly and get truly fat fucked, you may make new fat cells that aren't going away ever.

What bf% for males would you consider fat fucked?

[lylemcd]

When you get to 15%, certain things start going south in terms of insulin resistance, etc. 20% and you're officially a fat fuck IMO.