I had one on my foot that wasn't bothering me too bad. I mentioned it during a regular checkup and he offered to freeze it off with liquid nitrogen. As I am on my feet all day, I passed. A month or so later I was researching a medication prescribed by my dermatologist for sun-damaged skin, (5-fluorouracil cream or 5-FU for short). I came across several articles about treating plantar warts with it so I tried it. Wart went away.
(The dermatologist had told me apply it as needed to sun-damage spots so I figured it wouldn't be too dangerous to try it on the wart.)
Here is one study, Google will give several more.
http://www.ncbi.nlm.nih.gov/pubmed/16703777
Topical 5% 5-fluorouracil cream in the treatment of plantar warts: a prospective, randomized, and controlled clinical study.
Salk RS, Grogan KA, Chang TJ.
Source
Northern California Foot and Ankle Center, San Francisco and Santa Rosa, CA, USA.
drsalk@yahoo.com
Abstract
Topical 5-fluorouracil (5-FU) is an antineoplastic antimetabolite that inhibits DNA and RNA synthesis, thereby preventing cell replication and proliferation. This mechanism of action may allow topical 5-FU to be utilized in the treatment of human papilloma virus (HPV). We conducted a study comparing 5% 5-FU cream under tape occlusion versus tape occlusion alone in 40 patients presenting with plantar warts. Nineteen out of 20 patients (95%) randomized to 5% 5-FU with tape occlusion had complete eradication of all plantar warts within 12 weeks of treatment. The average time to cure occurred at 9 weeks of treatment. Three patients (15%) had a recurrence at the 6-month follow-up visit; accordingly, an 85% sustained cure rate was observed. It is concluded that use of topical 5% 5-fluorouracil cream for plantar warts is safe, efficacious, and accepted by the patient.
PMID:
16703777
[PubMed - indexed for MEDLINE]
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