It's an interesting question. Yes, mechanically, it there would be difference. The question is "How much?" From a perspective of simply looking at the effective length of the foot, the answer depends on A) size of the foot (length) and B) how much lift the heel gives. As an example, a 3/4" heel is going to have a much larger effect on a person with a size 4 foot than a size 14.
I need to think about it before I say more.