Why not starting strength and "clean keto" combined ?

[Mark Rippetoe]

"See carbs don't fatten us when UV light is present. Carbs fatten mammals at the end of summer/fall when UV light drops off a cliff. This is because we need strong UV light to drive electron flow from carbs within mitochondria. Without the UV, carb electrons leak, and produce more free radicals. This turns insulin ON to bring more glucose into cells to pack on fat. Overtime, as a mammals fat stores are filling up and swelling, and the cold hits, this is the signal for insulin resistance which does 2 things: 1) prevents more glucose from entering the cell and 2) keeps blood sugar high which acts as antifreeze. Then, the problem goes away when the mammal hibernates and activates the cold adapted/ketogenic pathway for winter."


Thanks for that. It is a very nice and simple technical analogy. This is a key point (as well as the post in general).

Is science education this bad? When it was only Kris, it was funny. Another argument for home school.

[kris90]

Is science education this bad? When it was only Kris, it was funny. Another argument for home school.

Nature never lies. Modern science = studies done in a lab under fake light and controlled temperature. Is nature like that? Nope. We have seasonal changes in the electromagnetic spectrum of sunlight as well as the strength of the earth's magnetic field that fluctuates with temperature changes (geothermal transitions).

So my argument is if you observe nature and mammals out in nature, you'll learn a hell of a lot more than relying on pubmed studies done in fake environments. Then again, we live in fake environments. So maybe people SHOULD eat fake food and fuel on carbs 24/7 in that environment. That will work until stem cell depletion occurs which leads to either 1) organ failure/sudden death or 2) cancer to try to slow down cell replacement.

[Mark Rippetoe]

Nature never lies.

Fascinating.

[Matt James]

Check out the Sherpas. They master their environment which is a cold, hypoxic environment.

The way I see it, is as mammals, and loosely coupled (Northern European) haplotype, we are designed to face cold. 10 C/50 F is the optimal temperature on the skin for activating the pathway. This is standard ground temperatures of mammals who hibernate. The cold-adapted pathway allowed mammals to survive the last extinction event (the KT). They connected to the ground to yield the earth's free electrons to keep their mitochondria humming, while using cold/thermogenesis and ketosis/fasting to survive. The birds used their mitochondrial capacity to fly and migrate to where the sun was. So we have a warm adapted and cold adapted pathway. But you are correct, nobody is using it today. One person who comes to mind though is Wim Hof.

"The Sherpa inhabit the Khumbu Valley of Nepal, and are descendants of a population that has resided continuously on the Tibetan plateau for the past ∼25,000 to 40,000 years. The long exposure of the Sherpa to an inhospitable environment has driven genetic selection and produced distinct adaptive phenotypes." Frontiers | Population History and Altitude-Related Adaptation in the Sherpa | Physiology You're talking about a tiny sliver of the modern day Nepalese population. Which does nothing to address the fact that a huge swath of early humans remained in warmer climates, and still do today.

[kris90]

"The Sherpa inhabit the Khumbu Valley of Nepal, and are descendants of a population that has resided continuously on the Tibetan plateau for the past ∼25,000 to 40,000 years. The long exposure of the Sherpa to an inhospitable environment has driven genetic selection and produced distinct adaptive phenotypes." Frontiers | Population History and Altitude-Related Adaptation in the Sherpa | Physiology You're talking about a tiny sliver of the modern day Nepalese population. Which does nothing to address the fact that a huge swath of early humans remained in warmer climates, and still do today.

Yes, but mammals are endotherms, and we have an entire biochemical program that we can still tap into that most humans never use today. It takes time to get there, but it is possible. Most humans live in a warm adapted state 24/7 eating a warm-adapted (i.e. carb) diet. All you need to do is look up Wim Hof, and you realise his abilities are built into the DNA of all eutherian mammals, which we are descendants of.

This is the pathway I am exploring and seeing if it can be leveraged for strength gains WITHOUT speeding up aging and cell cycles like warm-adapted/carbohydrate pathways tend to do. If lifting is not natural and depletes our lifeforce quicker, surely we should be exploring methods for preserving/recycling energy substrates to slow down this process. Yes, we are all going to die, but why not aim for performance AND longevity. I do believe the 2 can exist simultaneously within this ancient pathway.

The pathway is laid out nicely in this blog: Cold Thermogenesis 6: The Ancient Pathway – Dr. Jack Kruse

[Mark Rippetoe]

Are you married to this quack doctor, or do you just date him?

[kris90]

Are you married to this quack doctor, or do you just date him?

Nope he just opened my eyes to exploring other options when the high carb/bodybuilding lifestyle ruined me.

Unless you're an African American, you have a loosely coupled haplotype, so you may want to pay attention in how we are designed to work with our native environment. We are more leaky by nature, and the ketogenic diet offsets that leakiness, but we need cold thermogenesis to make it work. That's why fats provide 147 ATP per mole and glucose only provides 38 ATP.

The efficiency by which dietary calories are converted to ATP is determined by the coupling efficiency of OXPHOS. If the ETC is highly efficient at pumping protons out of the mitochondrial inner membrane and the ATP synthesis is highly efficient at converting the proton flow through its proton channel into ATP, then the mitochondria will generate the maximum ATP and the minimum heat per calorie consumed. These mitochondria are said to be tightly coupled. By contrast, if the efficiency of proton pumping is reduced and/or more protons are required to make each ATP by the ATP synthase, then each calorie burned will yield less ATP but more heat. Such mitochondria are said to be loosely coupled. Therefore, in an endothermic animal, the coupling efficiency determines the proportion of calories utilized by the mitochondrion to perform work versus those to maintain body temperature.

Source: A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine

More:

In addition to having to adapt to changing caloric availability due to seasonal changes, ancient human hunter-gathers had to adapt to the rigors of different climatic zones. While induction of UCP-1 in BAT and UCP-2 in muscle permits acute adaptation to thermal stress in rodents, this is not an adequate mechanism for long-term cold adaptation by humans. UCP-1 induction in BAT cannot generate sufficient heat to effectively regulate the temperature of the much larger human body. Therefore, as humans migrated into the more northern latitudes they had to adapt to the chronic cold using another mitochondrial strategy. It now appears that this global climatic adaptive strategy was achieved by the acquisition of mtDNA mutations that partially uncoupled OXPHOS and thus resulted in perpetually increased mitochondrial heat production.

[Mark Rippetoe]

Unless you're an African American, you have a loosely coupled haplotype, so you may want to pay attention in how we are designed to work with our native environment. We are more leaky by nature, and the ketogenic diet offsets that leakiness, but we need cold thermogenesis to make it work. That's why fats provide 147 ATP per mole and glucose only provides 38 ATP.

Fascinating.

[kris90]

This whole keto/paleo/vertical diet nonsense is just one big giant naturalistic fallacy.

„Because our ancestors did it!“ or „It’s natural!“ is just not a good argument.

Violence is natural. Not aging past 30 was natural. Hell, even cannibalism was „natural“ for some folks in the past.

Shoes are unnatural. Barbells are unnatural. Brain surgery is unnatural.

“Natural!“ or „Ancestors though!“ doesn’t mean shit.

And why do you think we have an explosion in chronic diseases today? Why are our children sicker than ever? It's because of the unnatural environment. That's my whole point.

So you can embrace this unnatural environment and succumb to chronic disease, or you can master your lifestyle and optimize your environment by reconnecting with nature to achieve optimal health and longevity. Point proven.

[Mark Rippetoe]

Both fascinating and devastating.