Mountain Home, Idaho Mayor Threatens to Fine and Arrest People but Uses Taxpayer-Funded Gym! - GregPruett.com
And the douche bags just keep on coming...
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Mountain Home, Idaho Mayor Threatens to Fine and Arrest People but Uses Taxpayer-Funded Gym! - GregPruett.com
And the douche bags just keep on coming...
Here's the latest data from your link:
Imgur: The magic of the Internet
That looks like a clear peak at the end of March.
So it looks like we have a two week lag between social distancing and peak death rate for NYC.
Here's a question for you:
Do you think that there is a causal relationship between the social distancing in NYC and the death rate peaking 2 weeks later?
If you do, then you implicitly understand that there are two processes at play here:
1) An exponential growth of infection.
2) The modulating influence of social distancing.
The net result (the shape of the curve) is a composition of these two processes. No sane epidemiologist is claiming unchecked exponential growth - there are often modulating influences in nature (and if there aren't, we can introduce them, like we do in the case of controlling a nuclear chain reaction with control rods).
Even if a community doesn't adapt their behaviour in the midst of an epidemic, herd immunity is control rod that checks the exponential growth.
There is no reason I know of that increasing a normal hemoglobin would reduce the risk of infection. The problem of low blood oxygen in pneumonia (including covid) comes from reduced oxygen exchange in the lungs, not from lack of red blood cells to carry it. Adding red blood cells would help marginally, if at all, and potentially causes some problems. And epogen would take far too long to be helpful.
Honestly, if you don’t know these basic things, it’s probably not worth your time to try to cure the most significant (hopefully) infectious disease of our lifetime. I like the outside-the-box thinking, however.
If this is true, might be interesting to figure out why. If it is indeed causally related to altitude, it might be through some genetic adaptation other than level of hemoglobin. This wiki link might have some relevant info.
Might even be that some populations incidentally inherited immune enhancements to their genome through high altitude selection (e.g. if population A came into contact with population B, and population B had adaptations to high altitude and to certain classes of viral pathogens, then both those sets of genes may be incorporated into population A even if only one of them (high altitude genes) was causally involved in the selection process.
But he has really nice arms.
Half of them just got there from California a couple of years ago, just long enough to fuck up local politics, but not within the scope of genetics. Like JF, I seen no mechanism by which an increase in H&H would mitigate the effects of a virus.
That's pretty good, Soule.
Yep, I re-read the original post after sending mine through, and realized the error after seeing the list of cities. I was thinking on a more global level.
If Soule's onto something, then you might expect the pattern to exist in countries by elevation, but I doubt there's an relationship.
Have you seen how the 代购 (daigou) problem has played into this? Really disgusting.
The media still seems to think the toilet paper hoarders were the big crooks. These gangs of 代购 "merchants" that exist to evade import/export taxes cleared out U.S., Aus and EU stockpiles of masks and PPE beginning in early January (often bragging about how the locals didn't know what was coming and there would be no masks left for them). They hoarded them, then have been selling back to the public at a 25X markup. (still available on Amazon and Ebay).
Good observation! I don't want to run the numbers to see if the correlation pans out, but the physiological effects of altitude is could be an important consideration that I had overlooked.
Would be interesting to better understand the exact correlation. Could get us officially out from under house arrest sooner.
I wonder how many patients who are suspected of dying of pneumonia are actually dying from cardiovascular complications.
The proposition of a newly elucidated porphyrin-dependent viral entry mechanism is interesting.
If the previously linked heme paper is correct, would we may be seeing deaths from a combination of:
-Systemic inflammatory response derived from abnormal heme metabolism
-Lower blood oxygen saturation due to a combination of lung damage, pneumonia, and reduced hematocrit (or hematocrit with impaired ability to interact with oxygen, CO2 and sugar)
-Porphyria-like pathophysiology
If the previously linked heme paper is incorrect, we still may have greater reason to speculate on or investigate the interaction of the virus with hemoglobin and its corresponding effects.