Originally Posted by
PMDL
The hormone response immediately around and right after training doesn't mean anything as far as protein synthesis changes in the muscle. I wrote up a big long tract about this.
Hormone changes correlate with a high stress being imposed on your system. They don't at all correlate with the time-course of increased MPS rates (which peak at 24-48 hours post-workout and stay elevated for upwards of 72 hours) or to the actual remodeling of muscle tissue.
There is a rationale for having a lot of protein before (especially), during, and after a workout, mainly due to the synergistic MPS-stimulating effects of circulating amino acids along with resistance training, but that has nothing to do with hormones. It's almost entirely a local-level muscular response.