This is exactly what I do. Lower frequency on the main lifts, but it doesn't effect me. My week is like this:
Mon - Bench + Chest/Bicep
Weds - Deads + Dead Asst
Fri - Press + Delts/Triceps
Mon - Back
Weds - Squat + Asst
Fri- Repeat
May squeeze in a Sat or Sun workout to shorten the cycle by a few days