Quercetin, is it good for the elderly?

[57bergstrm]

We have this discussion on the elderly blog. Whats your opinion Jordan?

[Jordan Feigenbaum]

There is some evidence to suggest that it may directly prevent atherosclerosis in rats via modulating cholesterol metabolism, help with allergies in humans, and may be a decent anti inflammatory. Additionally, it is biochemically plausible that it may be an anti-hypertensive. However, the jury is still out on the clinical effect- if any- of this supplement in humans based on my interpretation of the data. I don't know if I have a strong enough feeling one way or another currently, unfortunately.

[57bergstrm]

Thanks, for your opinion and lots of respect for your engagement. It means a lot for us geezers.

[vanslix]

FYI, rodent cholesterol metabolism does NOT resemble humans in the least. The research community has "cured" atherosclerosis in rodents about 300 different ways, none of which panned out in humans. Rodents are horrible models for CAD. Their cholesterol is different, their plaques are different, they don't form clots the same way, and most importantly, they don't get heart attacks from high cholesterol, diabetes, etc.

[Jordan Feigenbaum]

FYI, rodent cholesterol metabolism does NOT resemble humans in the least. The research community has "cured" atherosclerosis in rodents about 300 different ways, none of which panned out in humans. Rodents are horrible models for CAD. Their cholesterol is different, their plaques are different, they don't form clots the same way, and most importantly, they don't get heart attacks from high cholesterol, diabetes, etc.

You think it's cheese related?

[tnumrych]

You think it's cheese related?

God I hope not. I don't want to live a life without cheese and squats.