How can reaction force follow along? The target direction of your force is upwards, normal to the (horizontal) ground, and in the opposite direction of the gravity vector. You achieve this by pushing against the ground, and the ground pushes back up. If you're pushing directly downwards on an incline (the ground in this case is the incline of the sole of the shoe), the ground reaction force in the vertical direction is going to be reduced by a factor of the cosine of the angle of inclination.
Think about doing a standing vertical jump on an incline. You're not going to be able to jump as high. The ankle can't compensate so that the reaction force follows along.
Or so my thinking goes.