It is possible for this to happen and I have seen it occur. Thankfully, no one was injured. I don't like to have more than one 45 pound plate difference on each side. However, with a 7 foot barbell and a proper squat rack, you can have two 45s on one side and nothing on the other and it should be okay. For a bench press, I would not do that. I would stick to one 45. I am fairly conservative in this regard. I've never had a barbell flip on me.