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Thread: chronic inflammation

  1. #11
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    regarding the achilles thing, i never really did anything that resulted in anything severe or substantial. I went on a 2 mi run and probably went a little harder than i should have. My achilles was kinda sore the next day but not terrible.

    Just about every morning since, it is sore for the first 30min to an hour or so of walking around, then dies down, but there is always a sore spot there. It just seems strange to me that it's lingered for as long as it has without actually having done anything too dramatic to it.

  2. #12
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    Quote Originally Posted by Desp View Post
    Sundays after eating something high in gluten I would wake up Monday morning with my ankles and feet feeling swollen and my sinuses congested.
    I really hate to be unfashionable, but did you happen to take any before/after pictures of your swollen ankles?

    Many people will also notice a cognitive increase by removing gluten. It's so readily consumed without specifically trying so very few go without it, thus by many standards they always 'feel fine', not necessarily ever knowing the difference.[/QUOTE]

    Many people who expect to feel better when they remove gluten from their diet will, amazingly enough, feel better. They will certainly feel as though they are smarter.

  3. #13
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    Quote Originally Posted by Mark Rippetoe View Post
    I really hate to be unfashionable, but did you happen to take any before/after pictures of your swollen ankles?

    Many people will also notice a cognitive increase by removing gluten. It's so readily consumed without specifically trying so very few go without it, thus by many standards they always 'feel fine', not necessarily ever knowing the difference.
    Many people who expect to feel better when they remove gluten from their diet will, amazingly enough, feel better. They will certainly feel as though they are smarter.[/QUOTE]

    You say you've eaten paleo most of your life, rip-meat and eggs. Maybe you ingest so little gluten, it personally has no effect on you.

    just thinking aloud, nothing else.

  4. #14
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    Quote Originally Posted by Jonathon Sullivan View Post
    This would certainly explain why wheat and cereals have played such a small role in human history and the development of civilization.
    I'm not for or against gluten, as personally I have no problem with it. And yes, I have taken it out of my diet, and no, I didn't feel a difference. On the other hand, I have seen someone else do the same and feel better. Maybe psychosomatic, maybe not.

    That aside, it's perfectly possible that a food that people are slightly allergic could still be a benefit. When the choice is die of starvation or eat the readily harvested food, which might stuff you up a bit, the stuffed up people will have more energy to go a-conquering than the dead people.

  5. #15
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    Quote Originally Posted by Mark Rippetoe View Post
    I really hate to be unfashionable, but did you happen to take any before/after pictures of your swollen ankles?

    Many people will also notice a cognitive increase by removing gluten. It's so readily consumed without specifically trying so very few go without it, thus by many standards they always 'feel fine', not necessarily ever knowing the difference.
    Many people who expect to feel better when they remove gluten from their diet will, amazingly enough, feel better. They will certainly feel as though they are smarter.
    I've never bothered to take pictures, as I've eaten it enough times and have gotten out of bed barely being able to walk due to soreness to realize the connection and know I feel better without it.

    Regarding the cognitive performance, it's been measured through cognitive measurement tools, such as http://www.quantified-mind.com/ - Dave Asprey at The Bulletproof Exec has said it takes gluten 3 days to effect his cognitive performance. So one would expect if it's entirely placebo the decline might happen immediately after, or the next day, not 3 days later. He's also said for him it takes around 1 week for the negative effects to subside.

    Personally I don't measure the cognitive aspects of it, as I'm either so smart or so stupid not to know a difference or care. But I've seen many people say they notice or have measured a difference.

    There is other things as well, like the connection to thyroid autoimmune disorders and how the gluten protein resembles the thyroid, and how potentially it could make Hashimotos or Graves worse, or perhaps even cause it. One study suggests the immune response to gluten can last up to 6 months with people who are extremely intolerant, that being the case by skipping a day or two most people wouldn't even notice a difference, I would suggest at least two weeks if someone wanted to experiment. This is a pretty good article detailing what I've just explained - http://chriskresser.com/the-gluten-thyroid-connection

    Unfortunately this information is seen as more of a fad by hippies than anything else, but when one researches it and tries it them self the subject does have merit.

    Quote Originally Posted by Jonathon Sullivan View Post
    This would certainly explain why wheat and cereals have played such a small role in human history and the development of civilization.
    'Wheat Belly' by Dr. Davis explains how the wheat that is around today is very different from what they called wheat before.

    I think more importantly to understand is that ancient cultures prepared the grains very differently than how they are prepared today. Soaking sprouting and fermentation were all a staple of preparation. Most people are always told "Eat whole grain, it's better for you!" or to consume tons of oats, never realizing they're full of phytic acid, and anti nutrient that robs your body of nutrients due to the way they are prepared now days.

    I always opted for the brown rice over white, wheat bread over white, because it's "healthy". Then when my wife at age 29, in good health and ate 'clean' went to the dentist and they told her she had periodontal disease, it was incurable and they would have to do extensive cleanings and scrapings and it would never go away... I knew there had to be something wrong after I started researching it and realized how extremely common it is.

    I also had gingivitis and every time I went to the dentist my gums would bleed, floss more they say. Every time I floss my gums bleed, it never made a difference. Changed my diet... now I can floss anytime I choose and my gums never bleed. I knew there had to be something wrong with the requirement of flossing every day and brushing twice a day or your teeth would fall out attitude, yet throughout history brushing and flossing wasn't really available.

    I found this book - Cure Tooth Decay: Heal and Prevent Cavities with Nutrition - on Amazon, it's mainly about the Weston A Price foundation, and the research he did. It's extremely fascinating. I thought it was going to be a book just about tooth stuff, it's actually entirely about nutrition. Gee, who would think that cavities are almost 100 percent preventable, many are reversible and can heal them self, and it really has nothing to do with brushing or flossing.

    It seems nutrition also has a huge role on jaw development, and the reason why most people have their wisdom teeth removed due to crowding is not because they have too many teeth, they have too small of a jaw. The aforementioned book goes into detail regarding this.

    Back to the gluten connection, it seems things like sourdough bread almost completely eliminates the gluten protein from the enzymatic process, a staple of many cultures. Here's someone elses story on this - http://www.westonaprice.org/food-fea...bHV0ZW4iO30%3D

  6. #16
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    Quote Originally Posted by lewabbit View Post
    You say you've eaten paleo most of your life, rip-meat and eggs. Maybe you ingest so little gluten, it personally has no effect on you.
    But maybe I eat more gluten these days, and maybe it makes no difference at all. Maybe.

    Quote Originally Posted by Desp View Post
    ...toimmune disorders and how the gluten protein resembles the thyroid, and how potentially it could make Hashimotos or Graves worse, or perhaps even cause it. One study suggests the immune response to gluten can last up to 6 months with people who are extremely intolerant, that being the case by skipping a day or two most people wouldn't even notice a difference, I would suggest at least two weeks if someone wanted to experiment. This is a pretty good article detailing what I've just explained - http://chriskresser.com/the-gluten-thyroid-connection

    Unfortunately this information is seen as more of a fad by hippies than anything else, but when one resear...
    Fascinating.

  7. #17
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    Quote Originally Posted by Desp View Post
    ...back to the gluten connection
    Inflammation, including systemic inflammation (as opposed to just local inflammation), is measurable. Inflammation encompasses a number of different biological processes, but when we really MEAN inflammation -- in a formal sense -- it's not loosey goosey. A pathologist will use the word inflammation to refer to the increased presence of white blood cells in a particular tissue -- something that can be seen on a microscope slide -- i.e. the biopsy shows "acute inflammation" or "granulomatous inflammation". We can biochemically infer inflammation with certain blood tests -- c-reactive protein is an acute inflammatory protein, for instance. We can clinically infer inflammation if we see someone with a fever of 105 who is coughing up pus.

    So if you're going to invoke systemic inflammation from gluten (or whatever), then you'd be well advised to show what exactly is meant by the word inflammation.

  8. #18
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    Quote Originally Posted by Paul1 View Post
    Inflammation, including systemic inflammation (as opposed to just local inflammation), is measurable. Inflammation encompasses a number of different biological processes, but when we really MEAN inflammation -- in a formal sense -- it's not loosey goosey. A pathologist will use the word inflammation to refer to the increased presence of white blood cells in a particular tissue -- something that can be seen on a microscope slide -- i.e. the biopsy shows "acute inflammation" or "granulomatous inflammation". We can biochemically infer inflammation with certain blood tests -- c-reactive protein is an acute inflammatory protein, for instance. We can clinically infer inflammation if we see someone with a fever of 105 who is coughing up pus.

    So if you're going to invoke systemic inflammation from gluten (or whatever), then you'd be well advised to show what exactly is meant by the word inflammation.
    Yup.

  9. #19
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    for what it's worth, I have psoriasis and it has cleared up almost entirely since cutting gluten from my diet (I occasionally consume something containing gluten but not frequently). The only thing I've changed is my diet, and for 95% of the formerly affected areas, I don't even use the topical medicines that I had used for years. My uncle had a much more severe case, and his has almost completely cleared up.

    It's possible that it is an unexplained remission, unaffected by my change in diet, but since I've got other good reasons to avoid carby wheat I'm happy either way.

  10. #20
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    It's possible that gluten (gliadin, specifically) has negative effects aside from inflammation, however.

    Here's Robb Wolf on a study that suggests wheat increases gut permeability zonulin signaling in the epithelial barrier of the intestines in both Celiac and non-Celiac individuals.

    http://robbwolf.com/2011/01/12/hey-r...ets-are-bogus/

    I'm the first to admit there's a lot of words in there that I don't understand (i.e. WTF is immunoflourescence microscopy?), but I find this evidence compelling enough to eat my bacon and eggs toast-free. But everybody needs to determine their own dietary preferences based on their individual risk:reward profiles.

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